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2007-2012 GM Gen IV 4.8-6.2L EFI Harness – Throttle by Wire Part No 60526


Engine: 4.8, 5.3, 6.0, 6.2L
Trans.: 4L65E

Number of Circuits: 10 Fuses with 2 Ignition, 1 Cooling Fan & 1 Fuel Pump Relay
Harness Length: 4 Feet Between Engine and ECM
Fuse Type: Mini Blade
Firewall Passthrough: Grommet
Color Code Based:  2007 – 2012 Vortec Truck/SUV
Circuit Designations: Printed Wire Tags on all Connectors and Open Ended Wires

The Fuse Block Protects The Following Circuits:

  • ECM and Data Link Connector B+
  • ECM and Malfunction Indicator Lamp
  • Fuel Pump
  • Heated O2 Sensors
  • Ignition Coils
  • Injectors
  • Mass Airflow and Valve Lifter Oil Manifold (DOD)
  • TCM
  • TCM B+
  • Transmission
  • 40 Amp Cooling fan Relay and Circuit Breaker (ECM Activated)
  • 20 Amp Fuel Pump Relay
  • 40 Amp & 20 Amp Ignition Relays

This harness includes connections for the following components:

  • Accelerator Pedal Position Sensor
  • Alternator (Including a 4 gauge power wire)
  • Brake Switch
  • Cam Position/Cam Phazer Sensor
  • Cooling Fan
  • Crank Position Sensor
  • Data Link Connector
  • Driver/Pass Front O2 Sensors
  • Driver/Pass Knock Sensors
  • ECM
  • Engine Coolant Temperature
  • Fuel Pump
  • Grounds
  • Ignition Coils
  • Ignition Switch Signal
  • Injectors
  • Input Speed Sensor 4L80E/4L85E
  • Malfunction Indicator Lamp
  • MAP Sensor
  • Mass Airflow / Intake Air Temperature Sensor
  • Oil Pressure Sensor
  • PRNDL Switch
  • Reverse Lights
  • Starter
  • TCM
  • Throttle Body
  • Transmission
  • Valve Lifter Oil Manifold (DOD)
  • Vehicle Speed Sensor
  • VSS Output for Speedometer
Painless Part Number: 60526 Category: Product ID: 21211


This harness is standalone and is not intended to replace the OEM engine wiring.  Standalone harnesses are intended to run the designated engine & transmission only, generally when swapped into another vehicle.  

This harness is designed for use on any 2007-2012 4.8L, 5.3L, 6.0L, & 6.2L Vortec truck engines with throttle by wire. It is designed to use a factory ECM* & TCM*  and will operate engines with or without variable valve timing (VVT) and active fuel management (displacement on demand or DOD). This harness does not support flex fuel operation. Included with this harness are a 10-circuit weatherproof fuse block & mounting bracket, GM color-coded wires with labels, and all the required terminals and connectors for easy installation.

This standard-length harness allows four feet from the back of the intake manifold to where the fuse block and ECM mount. Perfect for those who plan to mount these components under the dash or in the glove box.

*We recommend checking the online manual for the full list of required mating parts before ordering as this harness does not work with all ECMs/TCMs

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